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Description:

An inherited metabolic disorder occurring especially in men, characterized by a raised but variable uric acid level, recurrent attacks of arthritis, deposition of crystals of uric acid in the connective tissues and articular cartilage which may progress to chronic arthritis.

Symptoms:

Sudden swelling, inflammation and intense pain in the joints, typically the big toe or ankle, sometimes the knee may be involved. In some cases, the above symptoms may be associated with alternating chills and fever.